Professeur adjoint

Roberto D. Fanganiello 

Biologie Régénérative, Biomatériaux, Bio-ingénierie tissulaire 

Pavillon de médecine dentaire


Formation universitaire
Post-doctoralen médecine régénérative et biomatériaux, Institut des biosciences et centre de recherche sur le génome humain et les cellules souches, Université de Sao Paulo 2016
Doctorat en Génétique Humaine, Département de Génétique et Évolution, Université de Sao Paulo 2010
Baccalauréat en Biologie, Institut des Biosciences, Université de Sao Paulo 2004


Publications récentes
  1. Ishiy FAA* , Fanganiello RD*#, Kobayashi GS , Kague E , Kuriki PS , Passos-Bueno MR # equal contribution *HQP. (2018). CD105 is regulated by hsa-miR-1287 and its expression is inversely correlated with osteopotential in SHED.BONE. Elsevier. ISSN: 8756-3282. 106: 112-120. 
  2. de Peralta MS , Mouguelar VS , Sdrigotti MA* , Ishiy FA , Fanganiello RD , Passos-Bueno MR , Coux G , Calcaterra NB *HQP. (2016). Cnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes.Cell Death & Disease. Nature Publishing Group. ISSN: 2041-4889. 7(10): e2397. 
  3. Yeh E , Atique R , Fanganiello RD , Sunaga DY , Ishiy FA* , Passos-Bueno MR * HQP. (2016). Cell Type-Dependent Nonspecific Fibroblast Growth Factor Signaling in Apert Syndrome.Stem Cells and Development. Mary Ann Liebert. ISSN: 1547-3287. 25(16): 1249-60. 
  4. Fanganiello RD , Ishiy FA* , Kobayashi GS , Alvizi L , Sunaga DY , Passos-Bueno MR * HQP. (2015). Increased In Vitro Osteopotential in SHED Associated with Higher IGF2 Expression When Compared with hASCs.Stem Cell Reviews and Reports. Springer. ISSN: 1550-8943. 11(4): 635-44. 
  5. Ishiy FA*# , Fanganiello RD#, Griesi-Oliveira K , Suzuki AM , Kobayashi GS , Morales AG , Capelo LP , Passos-Bueno MR # equal contribution * HQP. (2015). Improvement of In Vitro Osteogenic Potential through Differentiation of Induced Pluripotent Stem Cells from Human Exfoliated Dental Tissue towards Mesenchymal-Like Stem Cells.Stem Cells International. Hindawi. ISSN: 1687-9678. 2015: 249098. 
  6. Raposo-Amaral CE , Bueno DF , Almeida AB , Jorgetti V , Costa CC , Gouveia CH , Vulcano LC , Fanganiello RD , Passos-Bueno MR , Alonso N. (2014). Is bone transplantation the gold standard for repair of alveolar bone defects?. Journal of Tissue Engineering. Mary Ann Liebert, Inc. ISSN: 2152-4947. 5:2041731413519352. 
  7. Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome. Yeh E, Fanganiello RD, Sunaga DY, Zhou X, Holmes G, Rocha KM, Alonso N, Matushita H,   Wang   Y,   Jabs   EW,   Passos-Bueno   MR.   PLOS   ONE,   8(4):   e60439,   2013.   doi: 10.1371/journal.pone.0060439 
  8. FGFR2 Mutation Confers a Less Drastic Gain of Function in Mesenchymal Stem Cells Than in Fibroblasts. Yeh E, Atique R, Ishiy FAA, Fanganiello RD, Alonso N, Matushita H,da Rocha KM, Passos– Bueno MR. Stem Cell Reviews and Reports, v. 8, p.685-695, 2012. doi:10.1007/s12015-011-9327-6 
  9. Optimization of Parameters for a More Efficient Use of Adipose-Derived Stem Cells in Regenerative Medicine Therapies. Aguena M*, Fanganiello  RD*, Tissiani LAL, Ishiy FAA, Atique R, Alonso N, Passos-Bueno MR.* equal contribution. Stem Cells International, v. 2012, p. 1-7, 2012. doi: 10.1155/2012/303610 


Chapitres de livres 

  1. Nathalie Faucheux, Fabien Kawecki, Jessica Jann, François A. Auger, Roberto D. Fanganiello # and Julie Fradette# # Co-senior authors. (2020). Adipose-derived stromal/stem cells (ASCs) for bone tissue engineering applications. Kacey G. Marra, Peter J. Rubin. Scientific Principles of Adipose Stem Cells. 1: 90-120. Accepted, Elsevier Publishing 
  2. Sertié AL, Fanganiello RD , Passos-Bueno MR. (2017). Identificacao de mecanismos causativos de doencas geneticas humanas (Identification of human genetic disorders` mechanisms ). (chapter in Portuguese). Menck CFM, Van Sluys MA (Org.). Genética Molecular Básica: dos genes aos genomas (book in Portughese).  Published, Guanabara Koogan LTDA (Rio de Janeiro, Brazil) 
  3. Passos-Bueno MR, Fanganiello RD , BertolaDSertié AL. (2017). Mecanismos de doenças genéticas (chapter in Portuguese). (Mechanisms of genetic disorders). CFM, Van Sluys MA (Org.).Genética Molecular Básica: dos genes aos genomas. (book in Portughese). Published, Guanabara Koogan LTDA (Rio de Janeiro,Brazil) 


Conférences et communications scientifiques récentes
  1. nanometric calcium phosphate coating over titanium in association with stromal cells from human deciduous teeth to improve bone tissue formation and regeneration.7th International Symposium on Surfaces and Interfaces for Biomaterials (ISSIB). Session 1B: Biointerfaces I. 2019, Quebec City, QC, Canada, Quebec City, Canada 
  2. An introduction to stem cell-based regenerative medicine and dentistry. 7th International Symposium on Surfaces and Interfaces for Biomaterials (ISSIB). Pre-Conference Tutorials, Session 3 – Surfaces and Interfaces for biology and biosensors. 2019, Quebec City, QC, Canada, Quebec City, Canada 
  3. Advances in Stem Cell-Based Regenerative Medicine, Regenerative Dentistry, and Tissue Bioengineering. King Abdulaziz University 5th International Dental Conference. 2019, Jeddah, Saudi Arabia., Jeddah, Saudi Arabia 
  4. Establishing a Cell Technology Center and Stem Cell Biobank in South America.King Abdulaziz University 5th International Dental Conference. 2019, JeddahSaudi Arabia., JeddahSaudi Arabia 
  5. Tissue Bio-Engineering and its applications in Regenerative Medicine and Regenerative Dentistry. King Abdulaziz University 5th International Dental ConferenceJeddahSaudi Arabia 
  6. Educational pathways in Anaplastology. International Anaplastology Association`s 33rd Annual Conference. 2019, Scottsdale, AZ, USA., Scottsdale, United States 
  7. Introduction to Tissue Engineering, Regenerative Medicine and Dentistry. King’s College Summer Programme, Pre-University Course – « The Human Body », Session 2. 2019, London, London, United Kingdom, London, United Kingdom 
  8. Células Madres en Odontologia. XL Congresso de la Federación Odontológica de Centroamérica y Panamá (FOCAP). 2018, Managua, Nicaragua 
  9. Putting Stem Cells to Use Today. International Conference on BioMaterialsBioEngineering and BioTheranostics (BioMET 2018). Pre-Conference Workshop, Session 1 – Stem Cells. 2018, Vellore, India 
  10. Molecular events underlying heterogeneity in the osteopotential of human mesenchymal cells. International Conference on BioMaterialsBioEngineering and BioTheranostics (BioMET 2018). 2018, Vellore, India 
  11. Stem cells from human deciduous teeth associated with a nanometric calcium phosphate coating to improve bone tissue regeneration. International Anaplastology Association`s 31 st Annual Conference. 2017, Minneapolis, MN, USA. 
  12. Mesenchymal Stem Cells in Bone and Cartilage Regeneration.International Anaplastology Association`s 30 th Annual Conference. 2016, Fort Worth, USA. 
  13. Increased osteopotential in SHED associated with higher IGF2 expression when compared with hASCs .International Anaplastology Association`s 29 th Annual Conference. 2015, Rio de Janeiro, Brazil 
  14. Differentially expressed genes associated with higher osteogenic potential of human mesenchymal stem cells. International Society of Stem Cells Research Meeting, 2013. Boston, Massachusetts, USA. 
  15. Comparison of the osteogenic potential of adult stem cells from different sources. American Society of Human Genetics Meeting, 2012. San Francisco, California, USA. 
  16. Scanning of biomaterial composition and microstructure for human adult stem cells association and optimization of large bone defects regeneration. 9th International Society of Stem Cell Research Annual Meeting, 2011. Toronto, Ontario, Canada.